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One Slide Fits All: The Versatility of Slide Tracheoplasty Utilizing Cardiopulmonary Bypass Support for Airway Reconstruction in Children
Peter B. Manning1, Michael J. Rutter2, Asher Lisec3, Bradley S. Marino3
1 Cardiothoracic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; 2 Otorhinolaryngology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; 3 Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH

Objective: Distal tracheal reconstruction in children is commonly associated with significant mortality and morbidity. Slide tracheoplasty with cardiopulmonary bypass (CPB) support uses all native tissue allowing growth potential and results in a more stable airway, facilitating early extubation. The purpose of this study is to describe our results with this approach and identify predictors for adverse outcomes.
Methods: Patients undergoing slide tracheoplasty with CPB from 4/01-8/09 were reviewed. Preoperative characteristics, operative variables, and outcome measures [mortality, total hospital length of stay (LOS), and significant airway reintervention (>1 endoscopic dilation, stenting, and/or tracheal re-operation)] were collected. Predictors of worse outcomes were identified using bivariate analysis. Multivariable modeling was performed for predictors of prolonged LOS.
Results: The cohort included 76 patients (median age 8.7 months, 7d-20yrs); 71 (93%) had congenital tracheal lesions and 19 (25%) had prior tracheal operations. Length of tracheal pathology was <50%, 50-80%, and > 80% of the total tracheal length in 22, 35, and 19 patients respectively. 45 patients had associated cardiac or great vessel anomalies; 23 patients had simultaneous repair of a cardiovascular anomaly at the time of tracheal reconstruction. Median CPB time was 95 min (range 49-318) for the entire group and 86 min for tracheoplasty only. 47 (62%) patients were extubated within 48 hours of their operation. Median LOS was 19 days (range 7-119). 21 patients (28%) required significant airway reintervention during a median follow-up duration of 12 months (range 1m-7.8yrs). There were 4 deaths; 2 early and 2 late. In bivariate analysis, age (p=.015) and CPB duration (p=.029) were predictors of mortality, while duration of postoperative mechanical ventilation was associated with need for significant airway reintervention (p=.015). Multivariable analysis showed that preoperative ventilatory support (p<.001), longer CPB duration (p=.003), and the need for significant airway reintervention (p=.001) were predictors of longer LOS.
Conclusion: Slide tracheoplasty with CPB may be performed with low mortality in a diverse population of pediatric patients including those with full-length congenital stenosis, acquired lesions, and reoperative tracheoplasty. Utilizing this technique minimizes the need for early significant airway reintervention in the majority of patients.
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